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Why do I get so mad the week before my period?
Irritability is a symptom of the premenstrual disorders, either premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD). The American Psychiatric Association (APA) defines PMDD as a severe form of PMS in which symptoms of anger, irritability, and internal tension are prominent. In order to understand which condition you have, you will want to seek a diagnosis from your women’s health provider or gynecologist.
Many women with PMS or PMDD have normal concentrations of serum estrogen and progesterone, but may have an abnormal response to normal fluctuations of hormonal changes during the luteal phase or 2nd ½ of a cycle. The research suggests that the mood changes that women experience may be triggered by the interaction between cyclic changes in these hormones and the functioning of the brain’s neurotransmitters. The neurotransmitter that is most implicated in the manifestations of PMS is serotonin, although there is evidence to suggest the involvement of beta-endorphin, gamma-aminobutyric acid (GABA), and the autonomic nervous system.